Peptide Research

Promising animal data but insufficient human evidence to make strong recommendations. Those experimenting should understand they are essentially self-experimenting.

Interesting mechanism but human evidence is essentially absent. Those using are doing so based on animal studies and anecdote.

One of the better-studied GH peptides with established safety. Good starting point for those exploring GH optimization, but don't expect dramatic results.

The gold standard for GH peptides due to FDA approval and extensive clinical data. Higher cost but best evidence for efficacy and safety.

Attractive option for those wanting GH benefits without hunger/cortisol sides. Often paired with CJC-1295 for synergistic effect.

Convenient less-frequent dosing option. Popular in combination with Ipamorelin (the 'Ipa/CJC stack'). Start conservative with DAC version.

Best-studied oral GH secretagogue with robust evidence. The hunger increase is a dealbreaker for some. Monitor blood glucose if using.

FDA-approved option for women with low desire. Works differently than Viagra—addresses psychological arousal component. Nausea is the main limiting factor.

Well-supported for skin health topically. Injectable use for systemic anti-aging is more experimental. The gene expression data is intriguing but needs more clinical validation.

Fascinating anti-aging mechanism but evidence is still preliminary. Those using are early adopters taking on unknown risks for theoretical longevity benefits.

Exciting emerging peptide with strong mechanistic rationale. Too early for practical recommendations—currently in the 'promising but unproven' category.

One of the most advanced mitochondrial peptides in clinical development. Watch this space—could become an important anti-aging tool if trials succeed.

One of the better-studied supplements for skin and joint health. 10-15g daily with vitamin C is a reasonable protocol. Don't expect dramatic results.

Not essential for most healthy athletes eating adequate protein. May benefit those with gut issues, during illness, or in caloric deficit.

Inexpensive supplement with good safety profile. 3g before bed for sleep, or combine with collagen for connective tissue support.

Exciting animal longevity data but human evidence is limited. 1-3g daily appears safe. May be worth considering given low cost and good safety profile.

One of the more evidence-backed 'pump' supplements. 6-8g citrulline (or 8-10g citrulline malate) 30-60 min pre-workout. Benefits are modest but real.

Evidence-based for high-intensity exercise. 3-6g daily split into smaller doses to minimize tingling. Takes 2-4 weeks to work.

Not a priority for well-fed athletes. May benefit those cutting weight, recovering from injury, or elderly individuals at risk of sarcopenia.

If choosing between them, EAAs > BCAAs. But whole protein sources (whey, food) are more cost-effective for most people eating adequate protein.

Interesting mechanism but insufficient evidence for anti-aging claims. Astragalus root extract for general immune support is more established than telomere-specific claims.

Not a fat burner for most people. May benefit vegetarians, elderly, or those seeking recovery support. ALCAR form for cognitive benefits.